Excessive ibuprofen would cause chronic pain, study conducted with 98 patients found

The research is from the journal Science and may be the beginning to contribute to the knowledge of these drugs when it comes to pain treatment.

Recent research published in a prestigious medical journal suggests that anti-inflammatories such as Ibuprofen, which are used to alleviate acute pain, could turn it into chronic pain. This medicine is prescribed by doctors around the world to relieve acute pain, pain such as lumbar pain is treated with this popular medicine.

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According to the study published in Science, people who were treated with ibuprofen for acute pain had a 1.76 times greater risk of becoming chronic. The research was carried out at McGill University, in Canada, and the sample consisted of 98 patients with low back pain for a period of three months.

“Analysis of pain trajectories from human subjects reporting acute back pain to the UK Biobank identified an elevated risk of pain persistence for subjects taking NSAIDs. Thus, despite early analgesic efficacy, management of acute inflammation may be counterproductive to long-term outcomes for patients with low back pain; such prolongation was not seen with other analgesics.”

“For many decades it has been standard medical practice to treat pain with anti-inflammatory medications. But we found that this short-term fix could lead to longer-term problems,” says Jeffrey Mogil, a professor in the Department of Psychology at McGill University in Canada and one of the study’s authors.

Franziska Denk, a senior researcher at King’s College London, has commented on this study and says that there is a long way to go and research to worry about the conclusions of this research on NSAIDs. She said: “It would definitely be premature to make recommendations regarding people’s medication until we have the results of a prospectively designed clinical trial.”

“This study is a wonderful start to answering this question, but it now needs to be replicated and further investigated by other scientists,” agrees Dr. Franziska Denk, a professor at King’s College London, who was not involved in the research. .